Linked Life Data

12811967

Source:http://linkedlifedata.com/resource/pubmed/id/12811967

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
21
pubmed:dateCreated
2003-6-18
pubmed:abstractText
Three male schizophrenia patients, aged 41, 40 and 61 years respectively, who had undergone treatment without a satisfactory result, were treated with the antipsychotic clozapine. Diabetes mellitus developed within a period of several months to several years. The antipsychotic medication could be continued once the patients had been started on blood-glucose lowering medication. There seems to be an increased incidence of type-2 diabetes mellitus in patients with schizophrenia. It has been suggested that treatment with neuroleptics, especially atypical neuroleptics, provokes the onset of diabetes mellitus. The relatively young age (often < 50 years) at onset is a cause for concern. From a pathophysiological viewpoint, an increased prevalence of diabetic risk factors has been suggested for schizophrenia in addition to the toxic effect of neuroleptics in general. The possible consequences for the general health of this vulnerable group of patients warrant recommendations concerning the regular monitoring of these patients during treatment.
pubmed:language
dut
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0028-2162
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
147
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
993-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Schizophrenia and diabetes mellitus: not an improbable combination].
pubmed:affiliation
Centrum voor de GGZ Duin-en Bollenstreek, Langevelderweg 27, 2211 AB Noordwijkerhout. dcohen@rijngeestgroep.nl
pubmed:publicationType
Journal Article, English Abstract, Case Reports