Linked Life Data

12805548

Source:http://linkedlifedata.com/resource/pubmed/id/12805548

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5626
pubmed:dateCreated
2003-6-13
pubmed:abstractText
The SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) hypothesis suggests that pairs of proteins known as vesicle (v-) SNAREs and target membrane (t-) SNAREs interact specifically to control and mediate intracellular membrane fusion events. Here, cells expressing the interacting domains of v- and t-SNAREs on the cell surface were found to fuse spontaneously, demonstrating that SNAREs are sufficient to fuse biological membranes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1095-9203
pubmed:author
pubmed:issnType
Electronic
pubmed:day
13
pubmed:volume
300
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1745-9
pubmed:dateRevised
2007-3-19
pubmed:meshHeading
pubmed-meshheading:12805548-Animals, pubmed-meshheading:12805548-Antigens, Surface, pubmed-meshheading:12805548-COS Cells, pubmed-meshheading:12805548-Cell Fusion, pubmed-meshheading:12805548-Cell Membrane, pubmed-meshheading:12805548-Cercopithecus aethiops, pubmed-meshheading:12805548-Endoplasmic Reticulum, pubmed-meshheading:12805548-Glycosylation, pubmed-meshheading:12805548-Membrane Fusion, pubmed-meshheading:12805548-Membrane Proteins, pubmed-meshheading:12805548-Mutation, pubmed-meshheading:12805548-Nerve Tissue Proteins, pubmed-meshheading:12805548-Protein Binding, pubmed-meshheading:12805548-Protein Folding, pubmed-meshheading:12805548-Protein Structure, Tertiary, pubmed-meshheading:12805548-R-SNARE Proteins, pubmed-meshheading:12805548-Recombinant Fusion Proteins, pubmed-meshheading:12805548-Synaptosomal-Associated Protein 25, pubmed-meshheading:12805548-Syntaxin 1, pubmed-meshheading:12805548-Transfection
pubmed:year
2003
pubmed:articleTitle
Fusion of cells by flipped SNAREs.
pubmed:affiliation
Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 251, New York, NY 10021, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't