Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-6-13
pubmed:abstractText
The seroprevalences of anti-hantavirus antibodies were determined in 712 individuals (551 Indians, 140 Mennonites of German ancestry, and 21 Paraguayans of Spanish ancestry) inhabiting a region of western Paraguay in the Gran Chaco territory of South America. The overall seroprevalence of hantavirus infection among the 712 subjects, who were aged 2-80 years, was 42.7% (45.2% in the Indians and 34.2% in the non-Indians). Of the 672 subjects also checked for antibodies against Trypanosoma cruzi, 226 (33.6%) were seropositive for this protozoan parasite. The results of a multivariate regression analysis indicated that, after adjusting for age, sex, setting of residence (rural/urban) and infection with the human T-cell leukaemia/lymphoma virus type II (HTLV-II), a T. cruzi-seropositive individual was 1.73 times more likely to be hantavirus seropositive than a T. cruzi-seronegative individual. Living in a rural setting increased the risk of being hantavirus seropositive 2.17-fold. In both the Indians and non-Indian subpopulations, hantavirus seroprevalence increased with age in both sexes, but only in the non-Indian supopulation was this increase significantly greater in males than in females. Hantavirus seropositivity was significantly associated with thrombocytosis, even after adjusting for the relevant confounders.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0003-4983
pubmed:author
pubmed:issnType
Print
pubmed:volume
97
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
269-80
pubmed:dateRevised
2009-5-18
pubmed:meshHeading
pubmed-meshheading:12803858-Adolescent, pubmed-meshheading:12803858-Adult, pubmed-meshheading:12803858-Age Distribution, pubmed-meshheading:12803858-Aged, pubmed-meshheading:12803858-Aged, 80 and over, pubmed-meshheading:12803858-Blotting, Western, pubmed-meshheading:12803858-Chagas Disease, pubmed-meshheading:12803858-Child, pubmed-meshheading:12803858-Child, Preschool, pubmed-meshheading:12803858-Comorbidity, pubmed-meshheading:12803858-Endemic Diseases, pubmed-meshheading:12803858-Enzyme-Linked Immunosorbent Assay, pubmed-meshheading:12803858-Female, pubmed-meshheading:12803858-Hantavirus Infections, pubmed-meshheading:12803858-Humans, pubmed-meshheading:12803858-Indians, South American, pubmed-meshheading:12803858-Male, pubmed-meshheading:12803858-Middle Aged, pubmed-meshheading:12803858-Paraguay, pubmed-meshheading:12803858-Residence Characteristics, pubmed-meshheading:12803858-Seroepidemiologic Studies, pubmed-meshheading:12803858-Sex Distribution
pubmed:year
2003
pubmed:articleTitle
Hantavirus infection in people inhabiting a highly endemic region of the Gran Chaco territory, Paraguay: association with Trypanosoma cruzi infection, epidemiological features and haematological characteristics.
pubmed:affiliation
New Bolton Center, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USA. jfferrer@vet.upenn.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't