Source:http://linkedlifedata.com/resource/pubmed/id/12803858
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2003-6-13
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pubmed:abstractText |
The seroprevalences of anti-hantavirus antibodies were determined in 712 individuals (551 Indians, 140 Mennonites of German ancestry, and 21 Paraguayans of Spanish ancestry) inhabiting a region of western Paraguay in the Gran Chaco territory of South America. The overall seroprevalence of hantavirus infection among the 712 subjects, who were aged 2-80 years, was 42.7% (45.2% in the Indians and 34.2% in the non-Indians). Of the 672 subjects also checked for antibodies against Trypanosoma cruzi, 226 (33.6%) were seropositive for this protozoan parasite. The results of a multivariate regression analysis indicated that, after adjusting for age, sex, setting of residence (rural/urban) and infection with the human T-cell leukaemia/lymphoma virus type II (HTLV-II), a T. cruzi-seropositive individual was 1.73 times more likely to be hantavirus seropositive than a T. cruzi-seronegative individual. Living in a rural setting increased the risk of being hantavirus seropositive 2.17-fold. In both the Indians and non-Indian subpopulations, hantavirus seroprevalence increased with age in both sexes, but only in the non-Indian supopulation was this increase significantly greater in males than in females. Hantavirus seropositivity was significantly associated with thrombocytosis, even after adjusting for the relevant confounders.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-4983
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-80
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pubmed:dateRevised |
2009-5-18
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pubmed:meshHeading |
pubmed-meshheading:12803858-Adolescent,
pubmed-meshheading:12803858-Adult,
pubmed-meshheading:12803858-Age Distribution,
pubmed-meshheading:12803858-Aged,
pubmed-meshheading:12803858-Aged, 80 and over,
pubmed-meshheading:12803858-Blotting, Western,
pubmed-meshheading:12803858-Chagas Disease,
pubmed-meshheading:12803858-Child,
pubmed-meshheading:12803858-Child, Preschool,
pubmed-meshheading:12803858-Comorbidity,
pubmed-meshheading:12803858-Endemic Diseases,
pubmed-meshheading:12803858-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12803858-Female,
pubmed-meshheading:12803858-Hantavirus Infections,
pubmed-meshheading:12803858-Humans,
pubmed-meshheading:12803858-Indians, South American,
pubmed-meshheading:12803858-Male,
pubmed-meshheading:12803858-Middle Aged,
pubmed-meshheading:12803858-Paraguay,
pubmed-meshheading:12803858-Residence Characteristics,
pubmed-meshheading:12803858-Seroepidemiologic Studies,
pubmed-meshheading:12803858-Sex Distribution
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pubmed:year |
2003
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pubmed:articleTitle |
Hantavirus infection in people inhabiting a highly endemic region of the Gran Chaco territory, Paraguay: association with Trypanosoma cruzi infection, epidemiological features and haematological characteristics.
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pubmed:affiliation |
New Bolton Center, University of Pennsylvania, 382 West Street Road, Kennett Square, PA 19348, USA. jfferrer@vet.upenn.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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