Source:http://linkedlifedata.com/resource/pubmed/id/12798936
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2003-6-11
|
pubmed:abstractText |
We isolated a perchloric acid soluble protein from the post-mitochondria supernatant fraction of the rat lung and designated it as RLu-PSP1. The protein is soluble in 5% perchloric acid and was purified by ammonium sulfate fractionation and CM-Sephadex chromatography. The amino acid sequence of RLu-PSP was identical with that of rat liver PSP (RL-PSP). RLu-PSP inhibited protein synthesis in a rabbit reticulocyte lysate system. It was expressed mainly in cytoplasm of bronchioles and alveolar epithelial cells of the lung from 60-day-old rats. In 15-day-old rat embryos, the epithelial-lining of the terminal buds of the respiratory tree was immunopositive. The expression of RLu-PSP increased from the embryonic 15th day to the postnatal 40th day. This is the first report on the presence of a PSP in rat lung and on its involvement in the regulation of cellular growth and differentiation.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Heat-Shock Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Hrsp12 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Ribonucleases,
http://linkedlifedata.com/resource/pubmed/chemical/Serine Endopeptidases,
http://linkedlifedata.com/resource/pubmed/chemical/lysyl endopeptidase
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1096-4959
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
135
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
255-62
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12798936-Amino Acid Sequence,
pubmed-meshheading:12798936-Animals,
pubmed-meshheading:12798936-Base Sequence,
pubmed-meshheading:12798936-Embryo, Mammalian,
pubmed-meshheading:12798936-Heat-Shock Proteins,
pubmed-meshheading:12798936-Liver,
pubmed-meshheading:12798936-Lung,
pubmed-meshheading:12798936-Male,
pubmed-meshheading:12798936-Molecular Sequence Data,
pubmed-meshheading:12798936-Rabbits,
pubmed-meshheading:12798936-Rats,
pubmed-meshheading:12798936-Rats, Inbred BB,
pubmed-meshheading:12798936-Ribonucleases,
pubmed-meshheading:12798936-Serine Endopeptidases
|
pubmed:year |
2003
|
pubmed:articleTitle |
Purification and characterization of perchloric acid soluble protein from rat lung.
|
pubmed:affiliation |
Department of Veterinary Medicine, Faculty of Agriculture, Kagoshima University, Kagoshima 890-0065, Japan.
|
pubmed:publicationType |
Journal Article
|