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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11 Pt 2
|
| pubmed:dateCreated |
1992-12-16
|
| pubmed:abstractText |
In eight patients (age 62 +/- 6 years) a DDDR pacemaker was implanted for sick sinus syndrome (three cases) or second- and third-degree AV block (five cases). In five subjects chronotropic incompetence (maximal heart rate on effort < 110 beats/min) was present before implantation. One month after implantation the patients were randomized to DDDR or DDD pacing for 3 weeks each, with subsequent crossover, and at the end of each period a symptom limited cardiopulmonary exercise test (25 watts/2 min) was performed and the patients were requested to fill a symptoms questionnaire. Results: DDDR pacing, compared to DDD, was associated with higher maximal heart rates (127 +/- 20 vs 110 +/- 27 beats/min, P < 0.02), higher [VO2 max (25.4 +/- 6.1 vs 21.5 +/- 7.8 mL/kg/per min, P < 0.03) and higher VO2 at the anaerobic threshold (20.3 +/- 5.0 vs 15.8 +/- 4.9 mL/kg per min, P < 0.03), without significant differences in mean exercise time (526 +/- 193 vs 472 +/- 216 sec, NS). The increase in VO2 max obtained in DDDR versus DDD was significantly related to the increase in maximal heart rate (r = 0.72, P < 0.05) and the increase in VO2 at the anaerobic threshold obtained in DDDR versus DDD was related to the increase in heart rate at the anaerobic threshold (r = 0.81, P < 0.02).(ABSTRACT TRUNCATED AT 250 WORDS)
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0147-8389
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1908-13
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:1279570-Anaerobic Threshold,
pubmed-meshheading:1279570-Cardiac Pacing, Artificial,
pubmed-meshheading:1279570-Equipment Design,
pubmed-meshheading:1279570-Exercise Test,
pubmed-meshheading:1279570-Exercise Tolerance,
pubmed-meshheading:1279570-Female,
pubmed-meshheading:1279570-Heart Block,
pubmed-meshheading:1279570-Heart Rate,
pubmed-meshheading:1279570-Humans,
pubmed-meshheading:1279570-Male,
pubmed-meshheading:1279570-Middle Aged,
pubmed-meshheading:1279570-Pacemaker, Artificial,
pubmed-meshheading:1279570-Sick Sinus Syndrome,
pubmed-meshheading:1279570-Single-Blind Method
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Evaluation by cardiopulmonary exercise test of DDDR versus DDD pacing.
|
| pubmed:affiliation |
Institute of Cardiovascular Diseases, University of Bologna, Italy.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|