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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2003-6-5
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pubmed:abstractText |
Single nucleotide polymorphisms (SNPs) have been reported to influence cytokine production. Certain cytokine high producer genotypes have been associated with an increased risk for acute rejection and chronic allograft dysfunction (CAD) after transplantation. Our study evaluates SNP distribution for transforming growth factor-beta1 (TGF-beta1), interleukin-10 (IL-10), and tumor necrosis factor-alpha (TNF-alpha) in pediatric renal transplant recipients and control individuals and correlates them to corresponding intrarenal gene expression.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
314-20
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12787424-Adolescent,
pubmed-meshheading:12787424-Case-Control Studies,
pubmed-meshheading:12787424-Child,
pubmed-meshheading:12787424-Child, Preschool,
pubmed-meshheading:12787424-Chronic Disease,
pubmed-meshheading:12787424-Cytokines,
pubmed-meshheading:12787424-Female,
pubmed-meshheading:12787424-Gene Expression,
pubmed-meshheading:12787424-Graft Survival,
pubmed-meshheading:12787424-Humans,
pubmed-meshheading:12787424-Infant,
pubmed-meshheading:12787424-Interleukin-10,
pubmed-meshheading:12787424-Kidney,
pubmed-meshheading:12787424-Kidney Diseases,
pubmed-meshheading:12787424-Kidney Transplantation,
pubmed-meshheading:12787424-Male,
pubmed-meshheading:12787424-Polymorphism, Single Nucleotide,
pubmed-meshheading:12787424-Transforming Growth Factor beta,
pubmed-meshheading:12787424-Transforming Growth Factor beta1,
pubmed-meshheading:12787424-Tumor Necrosis Factor-alpha
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pubmed:year |
2003
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pubmed:articleTitle |
Cytokine single nucleotide polymorphisms and intrarenal gene expression in chronic allograft nephropathy in children.
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pubmed:affiliation |
Childrens' Hospital, Hannover Medical School, Hannover, Germany. anettemelk@yahoo.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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