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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2003-6-5
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pubmed:abstractText |
Terminal deoxynucleotidyltransferase (TdT) is a DNA polymerase that enhances the Ig and TcR gene diversity in the N region at the junctions of variable (V), diversity (D) and joining (J) segments in B- and T-cells. TdT synthesizes the N region in concert with many proteins including DNA-PKcs, Ku70 and Ku86. To elucidate the molecular mechanism of the N region synthesis, we first attempted to isolate the genes with products that directly interact with TdT.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1356-9597
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
559-71
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12786946-Amino Acid Sequence,
pubmed-meshheading:12786946-Cellulose,
pubmed-meshheading:12786946-Chromatin,
pubmed-meshheading:12786946-DNA,
pubmed-meshheading:12786946-DNA Nucleotidylexotransferase,
pubmed-meshheading:12786946-Histones,
pubmed-meshheading:12786946-Humans,
pubmed-meshheading:12786946-Molecular Sequence Data,
pubmed-meshheading:12786946-Molecular Weight,
pubmed-meshheading:12786946-Nuclear Proteins,
pubmed-meshheading:12786946-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:12786946-Saccharomyces cerevisiae,
pubmed-meshheading:12786946-Sequence Deletion,
pubmed-meshheading:12786946-Two-Hybrid System Techniques
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pubmed:year |
2003
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pubmed:articleTitle |
Terminal deoxynucleotidyltransferase forms a ternary complex with a novel chromatin remodeling protein with 82 kDa and core histone.
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pubmed:affiliation |
Faculty of Science and Technology, Department of Applied Biological Science, Tokyo University of Science, Noda, Chiba 278-8510, Japan.
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pubmed:publicationType |
Journal Article
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