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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2003-6-4
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pubmed:abstractText |
Human serum paraoxonase eliminates carcinogenic lipid-soluble radicals. Because expression of the main human paraoxonase gene PON1 varies widely in humans, certain PON1 polymorphisms might be associated with increased risks of cancer. We sought new functional mutations in PON1 and determined whether known or new PON1 mutations were associated with the risk for prostate cancer in a prospective, random, population-based sample of Finnish men and in a case-control study.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1460-2105
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pubmed:author |
pubmed-author:HakkarainenAnnaA,
pubmed-author:KaikkonenJariJ,
pubmed-author:KallioniemiOlli-POP,
pubmed-author:LehtimäkiTerhoT,
pubmed-author:MarchesaniMarjaM,
pubmed-author:MatikainenMikaM,
pubmed-author:PukkalaEeroE,
pubmed-author:SalonenJukka TJT,
pubmed-author:SchleutkerJohannaJ,
pubmed-author:SeppäläEijaE,
pubmed-author:TuomainenTomi-PekkaTP,
pubmed-author:UimariPekkaP
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pubmed:issnType |
Electronic
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pubmed:day |
4
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
812-8
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pubmed:dateRevised |
2010-4-29
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pubmed:meshHeading |
pubmed-meshheading:12783936-Aged,
pubmed-meshheading:12783936-Alleles,
pubmed-meshheading:12783936-Aryldialkylphosphatase,
pubmed-meshheading:12783936-Case-Control Studies,
pubmed-meshheading:12783936-Esterases,
pubmed-meshheading:12783936-Finland,
pubmed-meshheading:12783936-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:12783936-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:12783936-Genotype,
pubmed-meshheading:12783936-Heterozygote,
pubmed-meshheading:12783936-Humans,
pubmed-meshheading:12783936-Incidence,
pubmed-meshheading:12783936-Isoleucine,
pubmed-meshheading:12783936-Male,
pubmed-meshheading:12783936-Middle Aged,
pubmed-meshheading:12783936-Mutation,
pubmed-meshheading:12783936-Odds Ratio,
pubmed-meshheading:12783936-Polymorphism, Genetic,
pubmed-meshheading:12783936-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:12783936-Prospective Studies,
pubmed-meshheading:12783936-Prostatic Neoplasms,
pubmed-meshheading:12783936-Risk Assessment,
pubmed-meshheading:12783936-Risk Factors,
pubmed-meshheading:12783936-Sampling Studies,
pubmed-meshheading:12783936-Valine
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pubmed:year |
2003
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pubmed:articleTitle |
New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.
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pubmed:affiliation |
Oy Jurilab Ltd., Kuopio, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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