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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2003-6-3
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pubmed:abstractText |
The genetic basis of schizophrenia is obscure. In an XX male patient with schizophrenia we previously showed that one X;Y translocation breakpoint was in pseudoautosomal region 1 (PAR1) with the effect that the proximal segment of PAR1 from the PAR1 boundary to acetylserotonin N-methyl transferase (ASMT) distally was triplicated in this patient. This study determined whether dosage imbalances of X-Y homologous regions in general are associated with schizophrenia.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0955-8829
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-9
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pubmed:dateRevised |
2010-9-1
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pubmed:meshHeading |
pubmed-meshheading:12782970-Aneuploidy,
pubmed-meshheading:12782970-Antigens, CD,
pubmed-meshheading:12782970-Base Sequence,
pubmed-meshheading:12782970-Cell Adhesion Molecules,
pubmed-meshheading:12782970-Chromosome Mapping,
pubmed-meshheading:12782970-Chromosomes, Human, X,
pubmed-meshheading:12782970-Chromosomes, Human, Y,
pubmed-meshheading:12782970-DNA Primers,
pubmed-meshheading:12782970-Gene Dosage,
pubmed-meshheading:12782970-Humans,
pubmed-meshheading:12782970-Membrane Proteins,
pubmed-meshheading:12782970-Polymerase Chain Reaction,
pubmed-meshheading:12782970-R-SNARE Proteins,
pubmed-meshheading:12782970-Schizophrenia,
pubmed-meshheading:12782970-Translocation, Genetic
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pubmed:year |
2003
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pubmed:articleTitle |
Quantitation of X-Y homologous genes in patients with schizophrenia by multiplex polymerase chain reaction.
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pubmed:affiliation |
University of Oxford, Department of Psychiatry, Warneford Hospital, Oxford, UK. norman.ross@psychiatry.ox.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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