Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2003-6-3
pubmed:abstractText
Pyoverdines (PVDs) are complex siderophores produced by members of the fluorescent Pseudomonas. They comprise a dihydroxyquinoline fluorescent chromophore joined to a peptide of remarkably variable length and composition. In Pseudomonas aeruginosa, PVDs also function as signal molecules for the production of virulence factors. Genes responsible for the biosynthesis, excretion, uptake and regulation of these high-affinity siderophores are located either at a single locus or at up to three different loci in the genomes of the four pseudomonads analyzed. The peptide backbone of PVD is assembled by non-ribosomal peptide synthetases (NRPSs) and modified by accessory enzymes in the cytoplasm, and probably the periplasm. Regulation of PVD production and uptake depends on two extracytoplasmic sigma factors (ECF-sigmas), PvdS and FpvI, together with one anti-sigma, FpvR.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0966-842X
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-200
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Genomics of pyoverdine-mediated iron uptake in pseudomonads.
pubmed:affiliation
The Institute for Genomics Research, Pathogen Functional Genomics Resource Center, 9712 Medical Center Drive, Rockville, MD 20850, USA.
pubmed:publicationType
Journal Article