Source:http://linkedlifedata.com/resource/pubmed/id/12781010
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2003-6-3
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pubmed:abstractText |
Adventure travel is becoming more popular, increasing the likelihood of contact with unusual pathogens. We investigated an outbreak of leptospirosis in "Eco-Challenge" multisport race athletes to determine illness etiology and implement public health measures. Of 304 athletes, we contacted 189 (62%) from the United States and 26 other countries. Eighty (42%) athletes met our case definition. Twenty-nine (36%) case-patients were hospitalized; none died. Logistic regression showed swimming in the Segama River (relative risk [RR]=2.0; 95% confidence interval [CI]=1.3 to 3.1) to be an independent risk factor. Twenty-six (68%) of 38 case-patients tested positive for leptospiral antibodies. Taking doxycycline before or during the race was protective (RR=0.4, 95% CI=0.2 to 1.2) for the 20 athletes who reported using it. Increased adventure travel may lead to more frequent exposure to leptospires, and preexposure chemoprophylaxis for leptospirosis (200 mg oral doxycycline/week) may decrease illness risk. Efforts are needed to inform adventure travel participants of unique infections such as leptospirosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1080-6040
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pubmed:author |
pubmed-author:AshfordDavidD,
pubmed-author:BajaniMaryM,
pubmed-author:BancroftElizabethE,
pubmed-author:BettingerJulieJ,
pubmed-author:BraggSandraS,
pubmed-author:Eco-Challenge Investigation Team,
pubmed-author:KaiserRobynR,
pubmed-author:MaranoNinaN,
pubmed-author:MascolaLaureneL,
pubmed-author:PerkinsBradleyB,
pubmed-author:PopovicTanjaT,
pubmed-author:RosensteinNancyN,
pubmed-author:SejvarJamesJ,
pubmed-author:ShuttKathleenK,
pubmed-author:TapperoJordanJ,
pubmed-author:VugiaDucD,
pubmed-author:WinthropKevinK
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pubmed:issnType |
Print
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
702-7
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pubmed:dateRevised |
2010-12-17
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pubmed:meshHeading |
pubmed-meshheading:12781010-Adult,
pubmed-meshheading:12781010-DNA, Bacterial,
pubmed-meshheading:12781010-Disease Outbreaks,
pubmed-meshheading:12781010-Female,
pubmed-meshheading:12781010-Fever,
pubmed-meshheading:12781010-Fresh Water,
pubmed-meshheading:12781010-Humans,
pubmed-meshheading:12781010-Leptospira,
pubmed-meshheading:12781010-Leptospirosis,
pubmed-meshheading:12781010-Malaysia,
pubmed-meshheading:12781010-Male,
pubmed-meshheading:12781010-Middle Aged,
pubmed-meshheading:12781010-Risk Factors,
pubmed-meshheading:12781010-Sports,
pubmed-meshheading:12781010-Travel,
pubmed-meshheading:12781010-Water Microbiology
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pubmed:year |
2003
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pubmed:articleTitle |
Leptospirosis in "Eco-Challenge" athletes, Malaysian Borneo, 2000.
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pubmed:affiliation |
Division of Viral and Rickettsial Diseases, Mailstop A39, NCID, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA. zea3@cdc.gov
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pubmed:publicationType |
Journal Article
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