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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2003-7-14
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pubmed:abstractText |
We have previously shown that phospholipid oxidation products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine (ox-PAPC) inhibit lipopolysaccharide (LPS)-induced E-selectin expression and neutrophil binding in human aortic endothelial cells (HAECs). The current studies identify specific phospholipids that inhibit chemokine induction by Toll-like receptor-4 (TLR4) and -2 (TLR2) ligands inECs and macrophages.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1-palmitoyl-2-arachidonyl-3-phosphor...,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD36,
http://linkedlifedata.com/resource/pubmed/chemical/CAV1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Caveolin 1,
http://linkedlifedata.com/resource/pubmed/chemical/Caveolins,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8,
http://linkedlifedata.com/resource/pubmed/chemical/Lipopolysaccharides,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Phosphatidylcholines,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/TLR2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TLR4 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 2,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptor 4,
http://linkedlifedata.com/resource/pubmed/chemical/Toll-Like Receptors,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:BerlinerJudith AJA,
pubmed-author:ColeAmy LAL,
pubmed-author:KrutzikStephan RSR,
pubmed-author:LucasRobert MRM,
pubmed-author:ModlinRobert LRL,
pubmed-author:NakaiJunkoJ,
pubmed-author:SmartEric JEJ,
pubmed-author:SubbanagounderGanesamoorthyG,
pubmed-author:VoraDeven KDK,
pubmed-author:WaltonKimberly AKA,
pubmed-author:YehMichaelM
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1197-203
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:12775576-Animals,
pubmed-meshheading:12775576-Antigens, CD36,
pubmed-meshheading:12775576-Cattle,
pubmed-meshheading:12775576-Caveolae,
pubmed-meshheading:12775576-Caveolin 1,
pubmed-meshheading:12775576-Caveolins,
pubmed-meshheading:12775576-Cell Membrane,
pubmed-meshheading:12775576-Chemokine CCL2,
pubmed-meshheading:12775576-Endothelial Cells,
pubmed-meshheading:12775576-Humans,
pubmed-meshheading:12775576-Interleukin-1,
pubmed-meshheading:12775576-Interleukin-8,
pubmed-meshheading:12775576-Intracellular Membranes,
pubmed-meshheading:12775576-Lipopolysaccharides,
pubmed-meshheading:12775576-Macrophages,
pubmed-meshheading:12775576-Membrane Glycoproteins,
pubmed-meshheading:12775576-Phosphatidylcholines,
pubmed-meshheading:12775576-Receptors, Cell Surface,
pubmed-meshheading:12775576-Toll-Like Receptor 2,
pubmed-meshheading:12775576-Toll-Like Receptor 4,
pubmed-meshheading:12775576-Toll-Like Receptors,
pubmed-meshheading:12775576-Tumor Necrosis Factor-alpha
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pubmed:year |
2003
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pubmed:articleTitle |
Specific phospholipid oxidation products inhibit ligand activation of toll-like receptors 4 and 2.
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pubmed:affiliation |
Department of Medicine, University of California, Los Angeles, CA 90095-1732, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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