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pubmed-article:12775497pubmed:abstractTextIn this study, groups exposed to toluene either intentionally (glue sniffers) or unintentionally (shoe-workers) were compared. The groups were evaluated in terms of urinary levels of the toluene metabolites hippuric acid and o-cresol. Results were also compared with control values. Hippuric acid levels were determined by high performance liquid chromatography and o-cresol levels by gas liquid chromatography. The levels of hippuric acid and o-cresol were found to be statistically significantly higher in glue sniffers than in shoe-workers (p <0.001) or controls (p <0.001). In addition, the differences between the levels of urinary hippuric acid and o-cresol in the shoe-workers and in the controls were statistically significant (p <0.05 and p <0.001, respectively). These results suggest that extremely high levels of urinary hippuric acid and o-cresol indicate massive exposure to toluene.lld:pubmed
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pubmed-article:12775497pubmed:pagination119-27lld:pubmed
pubmed-article:12775497pubmed:dateRevised2004-11-17lld:pubmed
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pubmed-article:12775497pubmed:articleTitleDetermination of urinary hippuric acid and o-cresol levels as biological indicators of toluene exposure in shoe-workers and glue sniffers.lld:pubmed
pubmed-article:12775497pubmed:affiliationFaculty of Pharmacy, Department of Toxicology, Gazi University, Ankara, Turkey. ismetc@gazi.edu.trlld:pubmed
pubmed-article:12775497pubmed:publicationTypeJournal Articlelld:pubmed
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