|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2003-5-30
|
|
pubmed:abstractText |
In this study, groups exposed to toluene either intentionally (glue sniffers) or unintentionally (shoe-workers) were compared. The groups were evaluated in terms of urinary levels of the toluene metabolites hippuric acid and o-cresol. Results were also compared with control values. Hippuric acid levels were determined by high performance liquid chromatography and o-cresol levels by gas liquid chromatography. The levels of hippuric acid and o-cresol were found to be statistically significantly higher in glue sniffers than in shoe-workers (p <0.001) or controls (p <0.001). In addition, the differences between the levels of urinary hippuric acid and o-cresol in the shoe-workers and in the controls were statistically significant (p <0.05 and p <0.001, respectively). These results suggest that extremely high levels of urinary hippuric acid and o-cresol indicate massive exposure to toluene.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1354-750X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
119-27
|
|
pubmed:dateRevised |
2004-11-17
|
|
pubmed:meshHeading |
pubmed-meshheading:12775497-Adolescent,
pubmed-meshheading:12775497-Adult,
pubmed-meshheading:12775497-Aging,
pubmed-meshheading:12775497-Alcohol Drinking,
pubmed-meshheading:12775497-Biological Markers,
pubmed-meshheading:12775497-Child,
pubmed-meshheading:12775497-Chromatography, Gas,
pubmed-meshheading:12775497-Cresols,
pubmed-meshheading:12775497-Hippurates,
pubmed-meshheading:12775497-Humans,
pubmed-meshheading:12775497-Industry,
pubmed-meshheading:12775497-Male,
pubmed-meshheading:12775497-Middle Aged,
pubmed-meshheading:12775497-Occupational Exposure,
pubmed-meshheading:12775497-Shoes,
pubmed-meshheading:12775497-Smoking,
pubmed-meshheading:12775497-Solvents,
pubmed-meshheading:12775497-Substance Abuse Detection,
pubmed-meshheading:12775497-Substance-Related Disorders,
pubmed-meshheading:12775497-Toluene
|
|
pubmed:articleTitle |
Determination of urinary hippuric acid and o-cresol levels as biological indicators of toluene exposure in shoe-workers and glue sniffers.
|
|
pubmed:affiliation |
Faculty of Pharmacy, Department of Toxicology, Gazi University, Ankara, Turkey. ismetc@gazi.edu.tr
|
|
pubmed:publicationType |
Journal Article
|
