Source:http://linkedlifedata.com/resource/pubmed/id/12771410
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
Pt 6
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pubmed:dateCreated |
2003-5-28
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pubmed:abstractText |
To further characterize phocid herpesvirus type 1 (PhHV-1) at the molecular level, a cluster of genes comprising the complete unique short (Us) region of PhHV-1 has been cloned and sequenced. Within this region, ORFs were detected that code for the equivalent of the Us 2- protein of herpes simplex virus (HSV), a putative protein kinase, and for the glycoprotein equivalents gG, gD, gI and gE. In addition, two small ORFs downstream of gE, homologous to the Us 8.5 and Us 9 proteins of HSV were identified. Comparative analysis of the ORF encoding the gD equivalent of PhHV-1 identified the corresponding proteins of the alphaherpesviruses canine herpesvirus and, to lesser degree, feline herpesvirus as the closest relatives.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0022-1317
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1427-30
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12771410-Alphaherpesvirinae,
pubmed-meshheading:12771410-Animals,
pubmed-meshheading:12771410-Carnivora,
pubmed-meshheading:12771410-Cloning, Molecular,
pubmed-meshheading:12771410-Genes, Viral,
pubmed-meshheading:12771410-Multigene Family,
pubmed-meshheading:12771410-Open Reading Frames,
pubmed-meshheading:12771410-Phylogeny,
pubmed-meshheading:12771410-Seals, Earless,
pubmed-meshheading:12771410-Species Specificity,
pubmed-meshheading:12771410-Viral Proteins
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pubmed:year |
2003
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pubmed:articleTitle |
Genetic characterization of the unique short segment of phocid herpesvirus type 1 reveals close relationships among alphaherpesviruses of hosts of the order Carnivora.
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pubmed:affiliation |
Seal Rehabilitation and Research Centre, Hoofdstraat 94a, 9968 AG Pieterburen, The Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study
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