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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2003-5-27
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pubmed:abstractText |
DA-8159 is a pyrazolopyrimidinone derivative showing potent and selective phosphodiesterase 5 (PDE5) inhibition. In the previous study, DA-8159 induced a dose-dependent increase in the intracavernous pressure (ICP) in anaesthetized dogs. The aim of this study was to investigate the effects of DA-8159 on penile erection in conscious and acute spinal cord injured (ASCI) rabbits.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0302-2838
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
43
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
689-95
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:12767372-Administration, Oral,
pubmed-meshheading:12767372-Animals,
pubmed-meshheading:12767372-Disease Models, Animal,
pubmed-meshheading:12767372-Dose-Response Relationship, Drug,
pubmed-meshheading:12767372-Male,
pubmed-meshheading:12767372-Nissl Bodies,
pubmed-meshheading:12767372-Penile Erection,
pubmed-meshheading:12767372-Phosphodiesterase Inhibitors,
pubmed-meshheading:12767372-Pyrimidines,
pubmed-meshheading:12767372-Rabbits,
pubmed-meshheading:12767372-Spinal Cord Injuries,
pubmed-meshheading:12767372-Sulfonamides
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pubmed:year |
2003
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pubmed:articleTitle |
DA-8159, a new PDE5 Iihibitor, induces penile erection in conscious and acute spinal cord injured rabbits.
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pubmed:affiliation |
Research Laboratories of Dong-A Pharmaceutical Company, 47-5 Sanggal, Kiheung, Youngin, Kyunggi, 449-900 South Korea. kangkk@donga.co.kr
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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