Source:http://linkedlifedata.com/resource/pubmed/id/12762697
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2003-5-23
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pubmed:abstractText |
[structure: see text] By relying on the asymmetric aldol reactions of chiral ketones, a highly stereocontrolled synthesis of each of the C(17)-C(22) and C(23)-C(35) degradation fragments of reidispongiolide A has been achieved. This permits a configurational assignment of the complete C(17)-C(36) region of this antimitotic macrolide, along with providing advanced intermediates for a projected total synthesis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1523-7060
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
29
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1963-6
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:12762697-Animals,
pubmed-meshheading:12762697-Antineoplastic Agents,
pubmed-meshheading:12762697-Crystallography, X-Ray,
pubmed-meshheading:12762697-Ketones,
pubmed-meshheading:12762697-Macrolides,
pubmed-meshheading:12762697-Magnetic Resonance Spectroscopy,
pubmed-meshheading:12762697-Models, Molecular,
pubmed-meshheading:12762697-Molecular Conformation,
pubmed-meshheading:12762697-Porifera
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pubmed:year |
2003
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pubmed:articleTitle |
Toward the synthesis of reidispongiolide a: stereocontrolled synthesis of the C17-C22 and C23-C35 degradation fragments.
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pubmed:affiliation |
Department of Chemistry, University Chemical Laboratory, Lensfield Road, Cambridge CB2 1EW, United Kingdom. ip100@cam.ac.uk
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pubmed:publicationType |
Journal Article
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