Source:http://linkedlifedata.com/resource/pubmed/id/12762360
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-5-23
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pubmed:abstractText |
The diagnostic value of C-reactive protein (CRP) admission serum levels as an indicator of the aetiology of community-acquired pneumonia (CAP) was evaluated. A cohort of 1,222 patients with CAP was assessed. CRP levels were analysed in 258 patients with a single aetiological diagnosis. The mean CRP values in patients with pyogenic, atypical, viral and Legionella pneumophila pneumonia were: 16 mg x dL(-1), 13 mg x dL(-1), 14 mg x dL(-1) and 25 mg x dL(-1), respectively. CRP levels were not significantly different among patients outcome research team (PORT) groups (19 mg x dL(-1) in groups I-II, 16 mg x dL(-1) in group III and 16 mg x dL(-1) in groups IV-V). A cut-off point of 25 mg x dL(-1) had a sensibility, specificity, positive predictive value and negative predictive value of 0.6, 0.83, 0.3, and 0.94, respectively. After controlling for age and PORT score, the odds of having a CRP level >25 mg x dL(-1) was 6.9 times higher in patients with L. pneumophila pneumonia than in those with non-L. pneumophila pneumonia. Patients with Legionella pneumophila pneumonia had higher C-reactive protein levels than those with pneumonia of any other aetiology, independently of severity of infection. Being a cheap and readily available test, C-reactive protein may be a useful adjunctive procedure in the diagnosis of community-acquired pneumonia.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0903-1936
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
702-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12762360-Aged,
pubmed-meshheading:12762360-Analysis of Variance,
pubmed-meshheading:12762360-Biological Markers,
pubmed-meshheading:12762360-C-Reactive Protein,
pubmed-meshheading:12762360-Cohort Studies,
pubmed-meshheading:12762360-Community-Acquired Infections,
pubmed-meshheading:12762360-Female,
pubmed-meshheading:12762360-Humans,
pubmed-meshheading:12762360-Male,
pubmed-meshheading:12762360-Middle Aged,
pubmed-meshheading:12762360-Pneumonia,
pubmed-meshheading:12762360-Predictive Value of Tests,
pubmed-meshheading:12762360-Sensitivity and Specificity
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pubmed:year |
2003
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pubmed:articleTitle |
C-reactive protein levels in community-acquired pneumonia.
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pubmed:affiliation |
Dept of Infectious Diseases, Hospital Clinic, Barcelona, Spain. egarciav@clinic.ub.es
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pubmed:publicationType |
Journal Article
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