Linked Life Data

12757976

Source:http://linkedlifedata.com/resource/pubmed/id/12757976

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-5-21
pubmed:abstractText
The analysis of mice deficient in telomerase activity has allowed to directly test the relevance of telomeres and telomerase in tumor development and aging in the context of a mammalian organism. More recently, mice with impaired telomere capping due to abrogation of telomere-binding proteins have been also characterized. Here, I will discuss these studies, as well as their implications for putative therapies based of telomerase inhibition of telomerase re-introduction for cancer or age-related diseases, respectively.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0304-3835
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
194
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
183-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Telomeres in cancer and aging: lessons from the mouse.
pubmed:affiliation
Department of Immunology and Oncology, National Centre of Biotechnology, E-28049, Madrid, Spain. mblasco@cnb.uam.es <mblasco@cnb.uam.es>
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't