Source:http://linkedlifedata.com/resource/pubmed/id/12757503
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2003-5-21
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pubmed:abstractText |
Hepatitis B virus (HBV) may occasionally be transmitted through transfusion of blood units that are hepatitis B surface antigen (HBsAg) negative but HBV DNA positive. Children with beta-thalassemia are particularly susceptible to HBV because they receive multiple blood transfusions. These children have high infection rates despite vaccination against HBV. Post-vaccination infections may be a result of viruses harbouring surface (S)-gene mutations (e.g. G587A) in a region critical for reactivity to antibody to hepatitis B surface antigen (anti-HBs). The true prevalence of HBV in individuals with beta-thalassemia has not been studied previously.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0042-9007
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
292-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:12757503-Adolescent,
pubmed-meshheading:12757503-Adult,
pubmed-meshheading:12757503-Base Sequence,
pubmed-meshheading:12757503-Blood Transfusion,
pubmed-meshheading:12757503-Child,
pubmed-meshheading:12757503-Child, Preschool,
pubmed-meshheading:12757503-Female,
pubmed-meshheading:12757503-Hepatitis B,
pubmed-meshheading:12757503-Hepatitis B virus,
pubmed-meshheading:12757503-Humans,
pubmed-meshheading:12757503-India,
pubmed-meshheading:12757503-Infant,
pubmed-meshheading:12757503-Male,
pubmed-meshheading:12757503-Mutation, Missense,
pubmed-meshheading:12757503-Point Mutation,
pubmed-meshheading:12757503-Prevalence,
pubmed-meshheading:12757503-Viral Proteins,
pubmed-meshheading:12757503-beta-Thalassemia
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pubmed:year |
2003
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pubmed:articleTitle |
High frequency of hepatitis B virus infection in patients with beta-thalassemia receiving multiple transfusions.
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pubmed:affiliation |
Department of Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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