Linked Life Data

12755036

Source:http://linkedlifedata.com/resource/pubmed/id/12755036

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-5-20
pubmed:abstractText
The aim of this single photon emission computed tomography(SPECT) study was to determine the abnormality of the regional cerebral blood flow(rCBF) using a three-dimensional stereotactic surface projection (3 D-SSP) in 18 patients who were referred to the hospital because of forgetfulness. Two intergroup comparison by 3 D-SSP analysis was conducted based on MRI, kana pick-out test and Mini-Mental State Examination (MMSE) results. Of the MRI findings, in the brain atrophy group, rCBF was decreased in the posterior cingulate gyrus, medial temporal structure and parieto-temporal association cortex; these rCBF-decreased areas are similar to the Alzheimer disease pattern. In the group where the MMSE was normal but the kana pick-out test was abnormal, rCBF was decreased in the posterior cingulate gyrus and cinguloparietal transitional area. In the group where both the MMSE and kana pick-out test were abnormal, rCBF was decreased in the parieto-temporal association cortex, temporal cortex and medial temporal structure. These results suggest that 3 D-SSP analysis of the SPECT with MMSE and the kana pick-out test provides the possibility of early diagnosis of initial stage of Alzheimer's disease.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0006-8969
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
328-34
pubmed:dateRevised
2007-2-22
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[Evaluation by statistical brain perfusion SPECT analysis on MRI findings, kana pick-out test and Mini-Mental State Examination results in patients with forgetfulness].
pubmed:affiliation
Department of Neurological Surgery, Saiseikai Saijo Hospital, 269-1 Tsuitachi, Saijo-city, Ehime 793-0027, Japan.
pubmed:publicationType
Journal Article, English Abstract