Source:http://linkedlifedata.com/resource/pubmed/id/12746892
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2003-5-14
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pubmed:abstractText |
Susceptibility to rheumatoid arthritis (RA) is likely to involve several genes of weak effect, and consequently, individual studies may have insufficient power to detect linkage. Four major RA genome-wide linkage studies have been carried out, but apart from the well-established HLA susceptibility locus, none of the reported significant regions of linkage has been replicated. We applied a genome-search meta-analysis to 4 RA genome searches to assess linkage across studies, using published results.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1200-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:12746892-Arthritis, Rheumatoid,
pubmed-meshheading:12746892-Chromosomes, Human, Pair 16,
pubmed-meshheading:12746892-Genetic Linkage,
pubmed-meshheading:12746892-Genetic Predisposition to Disease,
pubmed-meshheading:12746892-Genome, Human,
pubmed-meshheading:12746892-HLA Antigens,
pubmed-meshheading:12746892-Humans
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pubmed:year |
2003
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pubmed:articleTitle |
Meta-analysis of four rheumatoid arthritis genome-wide linkage studies: confirmation of a susceptibility locus on chromosome 16.
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pubmed:affiliation |
Guy's Hospital, London, UK. sheila.fisher@kcl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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