rdf:type |
|
lifeskim:mentions |
umls-concept:C0007780,
umls-concept:C0023866,
umls-concept:C0026264,
umls-concept:C0030705,
umls-concept:C0042769,
umls-concept:C0085278,
umls-concept:C0205225,
umls-concept:C0220847,
umls-concept:C0282443,
umls-concept:C0684224,
umls-concept:C1533148,
umls-concept:C1552617
|
pubmed:issue |
2
|
pubmed:dateCreated |
2003-5-12
|
pubmed:abstractText |
We report the case of 36-year-old woman who came to us with a history of recurrent miscarriages and who was later diagnosed as having primary antiphospholipid syndrome (PAPS) and chronic hepatitis C virus (HCV) infection. The patient was referred to us with generalised seizures; cranial MRI revealed multiple embolic infarcts in both frontal lobes and a focal cortical infarct in the left frontoparietal lobe. Her echocardiography showed mitral valve vegetation and insufficiency. The patient was put on oral anticoagulant therapy and during her 8-month follow-up period no thrombotic events occurred. We report this case because it was the first in which PAPS, valvular disease, a cerebral embolic event and HCV infection were coexistent in the same patient. We also review other cases in which there was valvular vegetation and a cerebral ischaemic event associated with PAPS.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0770-3198
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
136-9
|
pubmed:dateRevised |
2005-11-16
|
pubmed:meshHeading |
pubmed-meshheading:12740679-Adult,
pubmed-meshheading:12740679-Antibodies, Anticardiolipin,
pubmed-meshheading:12740679-Anticoagulants,
pubmed-meshheading:12740679-Anticonvulsants,
pubmed-meshheading:12740679-Antiphospholipid Syndrome,
pubmed-meshheading:12740679-Carbamazepine,
pubmed-meshheading:12740679-Echocardiography, Doppler,
pubmed-meshheading:12740679-Endocarditis,
pubmed-meshheading:12740679-Epilepsy,
pubmed-meshheading:12740679-Female,
pubmed-meshheading:12740679-Hepatitis C,
pubmed-meshheading:12740679-Humans,
pubmed-meshheading:12740679-Intracranial Embolism,
pubmed-meshheading:12740679-Magnetic Resonance Imaging,
pubmed-meshheading:12740679-Mitral Valve Insufficiency,
pubmed-meshheading:12740679-Warfarin
|
pubmed:year |
2003
|
pubmed:articleTitle |
Mitral valve vegetation and cerebral emboli in a primary antiphospholipid syndrome patient who had hepatitis C virus infection: report of a case and review of the literature.
|
pubmed:affiliation |
Koca Sinan Mah, Sadik Ahmet Cad Varli Apt No: 25 Daire:2, Edirne, Turkey. onpamuk80@hotmail.com
|
pubmed:publicationType |
Journal Article,
Review,
Case Reports
|