| pubmed-article:12738765 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0521449 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0444626 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0003737 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C1522538 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0185026 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:12738765 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:12738765 | pubmed:issue | 30 | lld:pubmed |
| pubmed-article:12738765 | pubmed:dateCreated | 2003-7-21 | lld:pubmed |
| pubmed-article:12738765 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:abstractText | RbsD is the only protein whose biochemical function is unknown among the six gene products of the rbs operon involved in the active transport of ribose. FucU, a paralogue of RbsD conserved from bacteria to human, is also the only protein whose function is unknown among the seven gene products of the l-fucose regulon. Here we report the crystal structures of Bacillus subtilis RbsD, which reveals a novel decameric toroidal assembly of the protein. Nuclear magnetic resonance and other studies on RbsD reveal that the intersubunit cleft of the protein binds specific forms of d-ribose, but it does not have an enzyme activity toward the sugar. Likewise, FucU binds l-fucose but lacks an enzyme activity toward this sugar. We conclude that RbsD and FucU are cytoplasmic sugar-binding proteins, a novel class of proteins whose functional role may lie in helping influx of the sugar substrates. | lld:pubmed |
| pubmed-article:12738765 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12738765 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12738765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12738765 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12738765 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:12738765 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:12738765 | pubmed:author | pubmed-author:LeeWeontaeW | lld:pubmed |
| pubmed-article:12738765 | pubmed:author | pubmed-author:LeeHeung-SooH... | lld:pubmed |
| pubmed-article:12738765 | pubmed:author | pubmed-author:OhByung-HaBH | lld:pubmed |
| pubmed-article:12738765 | pubmed:author | pubmed-author:KimMin-SungMS | lld:pubmed |
| pubmed-article:12738765 | pubmed:author | pubmed-author:ShinJoonJ | lld:pubmed |
| pubmed-article:12738765 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12738765 | pubmed:day | 25 | lld:pubmed |
| pubmed-article:12738765 | pubmed:volume | 278 | lld:pubmed |
| pubmed-article:12738765 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12738765 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12738765 | pubmed:pagination | 28173-80 | lld:pubmed |
| pubmed-article:12738765 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:12738765 | pubmed:meshHeading | pubmed-meshheading:12738765... | lld:pubmed |
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| pubmed-article:12738765 | pubmed:meshHeading | pubmed-meshheading:12738765... | lld:pubmed |
| pubmed-article:12738765 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12738765 | pubmed:articleTitle | Crystal structures of RbsD leading to the identification of cytoplasmic sugar-binding proteins with a novel folding architecture. | lld:pubmed |
| pubmed-article:12738765 | pubmed:affiliation | Center for Biomolecular Recognition and Division of Molecular and Life Science, Department of Life Science, Pohang University of Science and Technology, Pohang, Kyungbuk, 790-784, Korea. | lld:pubmed |
| pubmed-article:12738765 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:12738765 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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