rdf:type |
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0002199,
umls-concept:C0018270,
umls-concept:C0021102,
umls-concept:C0025932,
umls-concept:C0045093,
umls-concept:C0086418,
umls-concept:C0086960,
umls-concept:C0162638,
umls-concept:C0178602,
umls-concept:C0205195,
umls-concept:C0205263,
umls-concept:C0205460,
umls-concept:C0225336,
umls-concept:C0235974,
umls-concept:C0392756,
umls-concept:C2698651
|
pubmed:issue |
5
|
pubmed:dateCreated |
2003-5-9
|
pubmed:abstractText |
We determined whether chronic administration of IFN-alpha at optimal biological dose inhibits angiogenesis of human pancreatic carcinoma growing in the pancreas of nude mice.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1078-0432
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
9
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1858-67
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:12738744-Animals,
pubmed-meshheading:12738744-Antigens, CD31,
pubmed-meshheading:12738744-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:12738744-Apoptosis,
pubmed-meshheading:12738744-Cell Division,
pubmed-meshheading:12738744-Deoxycytidine,
pubmed-meshheading:12738744-Dose-Response Relationship, Drug,
pubmed-meshheading:12738744-Endothelium, Vascular,
pubmed-meshheading:12738744-Fibroblast Growth Factor 2,
pubmed-meshheading:12738744-Humans,
pubmed-meshheading:12738744-Implants, Experimental,
pubmed-meshheading:12738744-Interferon-alpha,
pubmed-meshheading:12738744-Interleukin-8,
pubmed-meshheading:12738744-Male,
pubmed-meshheading:12738744-Matrix Metalloproteinase 9,
pubmed-meshheading:12738744-Mice,
pubmed-meshheading:12738744-Mice, Nude,
pubmed-meshheading:12738744-Neoplasm Transplantation,
pubmed-meshheading:12738744-Neoplasms, Experimental,
pubmed-meshheading:12738744-Pancreatic Neoplasms,
pubmed-meshheading:12738744-Survival Rate,
pubmed-meshheading:12738744-Tumor Cells, Cultured,
pubmed-meshheading:12738744-Vascular Endothelial Growth Factor A
|
pubmed:year |
2003
|
pubmed:articleTitle |
Administration of optimal biological dose and schedule of interferon alpha combined with gemcitabine induces apoptosis in tumor-associated endothelial cells and reduces growth of human pancreatic carcinoma implanted orthotopically in nude mice.
|
pubmed:affiliation |
Department of Cancer Biology, The University of Texas M. D. Anderson Cancer Center, Houston 77030, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|