| pubmed-article:12736523 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12736523 | lifeskim:mentions | umls-concept:C0282641 | lld:lifeskim |
| pubmed-article:12736523 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:12736523 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:12736523 | lifeskim:mentions | umls-concept:C0005052 | lld:lifeskim |
| pubmed-article:12736523 | lifeskim:mentions | umls-concept:C0332293 | lld:lifeskim |
| pubmed-article:12736523 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:12736523 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:12736523 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:12736523 | pubmed:dateCreated | 2003-5-8 | lld:pubmed |
| pubmed-article:12736523 | pubmed:abstractText | Transgene expression and skin tumorigenicity were investigated in transgenic TG-AC mice carrying the v-Ha-ras after treatment with benzo[a]pyrene (BP). Animals treated with 40 microg BP (x2/week/mouse) showed 100% tumor response after 25 weeks, as did 40% of the mice treated with 20 microg BP but 10 microg BP did not produce a tumor response. In the case of animals treated with 40 microg BP for 25 weeks, most of the tumors were proven to be carcinomas (80%, 4 out of 5 mice), and all tumors were shown to be positive in terms of transgene expression detected by in situ hybridization. These data suggest that BP was tumorigenic in a dose-dependent manner in TG-AC mice and that TG-AC mice were dependent on transgene expression during BP carcinogenesis. | lld:pubmed |
| pubmed-article:12736523 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12736523 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12736523 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:12736523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12736523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12736523 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12736523 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12736523 | pubmed:month | May | lld:pubmed |
| pubmed-article:12736523 | pubmed:issn | 0918-6158 | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:ParkYo AnYA | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:LeeByung MuBM | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:YooSun DongSD | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:KimHyung... | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:ParkKui LaeKL | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:KwackSeung... | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:HanSoon... | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:KimIn SunIS | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:ChoMyung... | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:KimKyu BongKB | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:AhnMi YoungMY | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:ChunSun AhSA | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:ChoiSul MinSM | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:SongHyun... | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:LeeKyung... | lld:pubmed |
| pubmed-article:12736523 | pubmed:author | pubmed-author:BaeHye JinHJ | lld:pubmed |
| pubmed-article:12736523 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12736523 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:12736523 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12736523 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12736523 | pubmed:pagination | 733-5 | lld:pubmed |
| pubmed-article:12736523 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:meshHeading | pubmed-meshheading:12736523... | lld:pubmed |
| pubmed-article:12736523 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12736523 | pubmed:articleTitle | Ras transgene expression in TG-AC mice treated with benzo[a]pyrene. | lld:pubmed |
| pubmed-article:12736523 | pubmed:affiliation | Division of Toxicology, College of Pharmacy, SungKyunKwan University, Chunchun-dong, Suwon, Kyonggi-do, South Korea. bmlee@skku.ac.kr | lld:pubmed |
| pubmed-article:12736523 | pubmed:publicationType | Journal Article | lld:pubmed |
