Linked Life Data

12731018

Source:http://linkedlifedata.com/resource/pubmed/id/12731018

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2003-5-5
pubmed:abstractText
The electrophoresis of a biological cell is analyzed theoretically. An entity, which is of amphoteric nature, is used to simulate its electrophoretic behavior. To reflect conditions of practical interest, we assume that the liquid phase contains mixed (a:b)+(c:b) electrolytes, where a and c are the valences of cations, and b is the valence of anions. We consider the case where the surface of a cell contains both bivalent acidic and monovalent basic functional groups, the dissociation/association of them yields fixed surface charge, and the multivalent cations in the liquid phase are allowed to combine with dissociated acidic functional groups, which has the effect of lowering the charge density on cell surface. The electrophoretic behaviors of a cell under various conditions are illustrated. The results obtained can be used to identify the types of functional groups that may be present on cell surface. On the other hand, if the surface functional groups involved in cell electrophoresis are known, then their density and the associated dissociation/association constants can be estimated from experimental data.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0173-0835
pubmed:author
pubmed:issnType
Print
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1338-46
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Electrophoresis of biological cells: charge-regulation and multivalent counterions association model.
pubmed:affiliation
Department of Chemical Engineering, National Taiwan University, Taipei, Taiwan, R.O.C. jphsu@ccms.ntu.edu.tw
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't