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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2003-5-5
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pubmed:abstractText |
70 kDa Heat shock proteins are involved in mucosal protecting reactions in the gut of patients with inflammatory bowel disease. Recently, a single nucleotide polymorphism (PstI, nucleotide 1267) was associated with intestinal perforations and formation of abscesses and fistulas in Japanese patients with Crohn's disease. Our purpose was to evaluate this phenomenon in Caucasian patients with Crohn's disease and to verify the clinical importance of this polymorphism.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0949-2321
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
120-4
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:12730033-Adolescent,
pubmed-meshheading:12730033-Adult,
pubmed-meshheading:12730033-Aged,
pubmed-meshheading:12730033-Child,
pubmed-meshheading:12730033-Crohn Disease,
pubmed-meshheading:12730033-Female,
pubmed-meshheading:12730033-Gene Frequency,
pubmed-meshheading:12730033-Genotype,
pubmed-meshheading:12730033-HSP70 Heat-Shock Proteins,
pubmed-meshheading:12730033-Homozygote,
pubmed-meshheading:12730033-Humans,
pubmed-meshheading:12730033-Male,
pubmed-meshheading:12730033-Middle Aged,
pubmed-meshheading:12730033-Polymorphism, Genetic,
pubmed-meshheading:12730033-Severity of Illness Index
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pubmed:year |
2003
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pubmed:articleTitle |
Heat-shock protein HSP70-2 genotypes in patients with Crohn's disease: a more severe clinical course with intestinal complications in presence of the PstI-polymorphism.
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pubmed:affiliation |
Medizinische Poliklinik, Klinikum der Universität - Innenstadt, Ludwig-Maximilians-Universität München, Germany.
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pubmed:publicationType |
Journal Article
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