Source:http://linkedlifedata.com/resource/pubmed/id/12729641
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2003-5-5
|
| pubmed:abstractText |
Dimeric vancomycin analogues based on a lead compound identified from a library of synthetic analogues of vancomycin have up to 60-fold greater activity than vancomycin against vancomycin-resistant Enterococcus faecium (VRE, VanA phenotype). Simplified analogues have also been prepared and found to maintain activity against VRE and have broad-spectrum antibiotic activity.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
May
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
19
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1683-6
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:12729641-Anti-Bacterial Agents,
pubmed-meshheading:12729641-Bacteria,
pubmed-meshheading:12729641-Combinatorial Chemistry Techniques,
pubmed-meshheading:12729641-Drug Resistance, Bacterial,
pubmed-meshheading:12729641-Enterococcus faecium,
pubmed-meshheading:12729641-Microbial Sensitivity Tests,
pubmed-meshheading:12729641-Structure-Activity Relationship,
pubmed-meshheading:12729641-Vancomycin
|
| pubmed:year |
2003
|
| pubmed:articleTitle |
Identification of potent and broad-spectrum antibiotics from SAR studies of a synthetic vancomycin analogue.
|
| pubmed:affiliation |
Center for New Directions in Organic Synthesis, Department of Chemistry, University of California, Berkeley 94720, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|