Linked Life Data

12727518

Source:http://linkedlifedata.com/resource/pubmed/id/12727518

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-5-2
pubmed:abstractText
Historical data, available in the literature, concerning the sites responsible for integrin-ligand binding and activation may now be transposed onto recently solved crystal structures of integrin dimers and functional domains. The data were obtained through studies of natural and engineered mutations within integrins, and analyses of the epitopes for function-altering monoclonal antibodies. In the past two years, this combining of structure and function has led to the development of novel hypotheses for the mechanisms of integrin regulation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0959-440X
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
236-43
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Mapping functional residues onto integrin crystal structures.
pubmed:affiliation
Wellcome Trust Centre for Cell-Matrix Research, School of Biological Sciences, University of Manchester, 2.205 Stopford Building, Oxford Road, United Kingdom. martin.humphries@man.ac.uk
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't