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12723941
Source:
http://linkedlifedata.com/resource/pubmed/id/12723941
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48
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0184511
,
umls-concept:C0220781
,
umls-concept:C0279516
,
umls-concept:C0441655
,
umls-concept:C0450254
,
umls-concept:C1449860
,
umls-concept:C1554080
,
umls-concept:C1706198
,
umls-concept:C1883254
pubmed:issue
10
pubmed:dateCreated
2003-5-1
pubmed:abstractText
A series of novel 6-O-substituted homopropargyl ketolides was synthesized and evaluated against various erythromycin-resistant pathogens. Promising in vitro antibacterial activity was demonstrated for compounds bearing this structural motif.
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/9716531
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Alkynes
,
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Bacterial Agents
,
http://linkedlifedata.com/resource/pubmed/chemical/Erythromycin
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0022-2623
pubmed:author
pubmed-author:CarterJustin JJJ
,
pubmed-author:DalyMelissa MMM
,
pubmed-author:EnglundErika EEE
,
pubmed-author:KeyesRobert FRF
,
pubmed-author:MaZhenkunZ
,
pubmed-author:NiliusAngela MAM
,
pubmed-author:StoneGreg GGG
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1795-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed-meshheading:12723941-Alkynes
,
pubmed-meshheading:12723941-Anti-Bacterial Agents
,
pubmed-meshheading:12723941-Drug Resistance, Bacterial
,
pubmed-meshheading:12723941-Erythromycin
,
pubmed-meshheading:12723941-Haemophilus influenzae
,
pubmed-meshheading:12723941-Microbial Sensitivity Tests
,
pubmed-meshheading:12723941-Staphylococcus
,
pubmed-meshheading:12723941-Structure-Activity Relationship
pubmed:year
2003
pubmed:articleTitle
Synthesis and antibacterial activity of 6-O-arylbutynyl ketolides with improved activity against some key erythromycin-resistant pathogens.
pubmed:affiliation
Infectious Disease Research, Abbott Laboratories, D47P, AP52N, 200 Abbott Park Road, Abbott Park, Illinois 60064-6217, USA. robert.keyes@abbott.com
pubmed:publicationType
Journal Article