Linked Life Data

12721351

Source:http://linkedlifedata.com/resource/pubmed/id/12721351

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2003-4-30
pubmed:abstractText
Although tissue engineering of articular cartilage is a promising approach for cartilage repair, it has been difficult to develop cartilaginous tissue in vitro that mimics the properties of native cartilage. Isolated chondrocytes grown in culture typically do not accumulate enough extracellular matrix, and the generated tissue possesses only a fraction of the mechanical properties of native cartilage. One potential explanation for this might be that the cells are grown in an environment that lacks the mechanical stimuli to which the chondrocytes are exposed in vivo. In this study, we compared the long-term effects of both dynamic compressive and shearing forces on cartilaginous tissue formation in vitro.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0021-9355
pubmed:author
pubmed:issnType
Print
pubmed:volume
85-A Suppl 2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
101-5
pubmed:dateRevised
2010-10-25
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Effect of biomechanical conditioning on cartilaginous tissue formation in vitro.
pubmed:affiliation
Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't