Linked Life Data

12718865

Source:http://linkedlifedata.com/resource/pubmed/id/12718865

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2003-4-29
pubmed:abstractText
Temporal difference learning has been proposed as a model for Pavlovian conditioning, in which an animal learns to predict delivery of reward following presentation of a conditioned stimulus (CS). A key component of this model is a prediction error signal, which, before learning, responds at the time of presentation of reward but, after learning, shifts its response to the time of onset of the CS. In order to test for regions manifesting this signal profile, subjects were scanned using event-related fMRI while undergoing appetitive conditioning with a pleasant taste reward. Regression analyses revealed that responses in ventral striatum and orbitofrontal cortex were significantly correlated with this error signal, suggesting that, during appetitive conditioning, computations described by temporal difference learning are expressed in the human brain.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0896-6273
pubmed:author
pubmed:issnType
Print
pubmed:day
24
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
329-37
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Temporal difference models and reward-related learning in the human brain.
pubmed:affiliation
Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, WC1N 3BG, London, United Kingdom. j.odoherty@fil.ion.ucl.ac.uk
pubmed:publicationType
Journal Article, Clinical Trial, Research Support, Non-U.S. Gov't