Allo-cell transplant rejection and autoimmune responses were associated with the presence of class II major histocompatibility complex (MHC II) molecules on cells. This paper studied the effect of Ribonuclease P (RNase P) against CIITA, which was a major regulator of MHCII molecules, on repressing the expression of MHCII molecules on hepatocyte.
Institute of Hematology, the Union Hospital, Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China. gh7311@yahoo.com.cn
