Source:http://linkedlifedata.com/resource/pubmed/id/12717519
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2003-4-28
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pubmed:abstractText |
Transplantation of allogenic bone marrow from HLA-identical sibs to patients with acute and chronic leukemia receiving immunosuppressive therapy is associated with the appearance of erythrocytes simultaneously carrying donor and recipient antigenic markers: AB0 system, rhesus factor and its subtypes, M and N antigens. Integration of genes responsible for each antigen is realized independently presumably at the level of stem cell, which ensures long-term (>3 years) repopulation of these erythrocytes. Experiments on inbred mice showed that transplantation of allogenic bone marrow is associated with an increase of chromosome number in 39% bone marrow cells 4 days after transplantation, which indicate the possibility of integration of whole chromosomes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-4888
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
135
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
73-6
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:12717519-Animals,
pubmed-meshheading:12717519-Bone Marrow Cells,
pubmed-meshheading:12717519-Bone Marrow Transplantation,
pubmed-meshheading:12717519-Epitopes,
pubmed-meshheading:12717519-Erythrocytes,
pubmed-meshheading:12717519-Female,
pubmed-meshheading:12717519-Humans,
pubmed-meshheading:12717519-Hybrid Cells,
pubmed-meshheading:12717519-Leukemia,
pubmed-meshheading:12717519-Metaphase,
pubmed-meshheading:12717519-Mice,
pubmed-meshheading:12717519-Mice, Inbred CBA
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pubmed:year |
2003
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pubmed:articleTitle |
Changes in antigenic characteristics of erythrocytes and number metaphase chromosome in bone marrow cells after experimental and clinical bone marrow transplantation.
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pubmed:affiliation |
Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow.
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pubmed:publicationType |
Journal Article
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