rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
1
|
pubmed:dateCreated |
2003-4-28
|
pubmed:abstractText |
Systemic oral administration of NT-0409, a new synthetic agonist of AMPA subtype glutamate receptor, to rats with chronic partial AF64A-induced deprivation of cholinergic functions improved their learning in a Morris water maze. NT-0409 is close to memantine by the effect on learning and, in contrast to cholinomimetic arisept, ensures longer retention of the developed habit.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0007-4888
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
135
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
48-51
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12717512-Alzheimer Disease,
pubmed-meshheading:12717512-Animals,
pubmed-meshheading:12717512-Aziridines,
pubmed-meshheading:12717512-Brain,
pubmed-meshheading:12717512-Choline,
pubmed-meshheading:12717512-Excitatory Amino Acid Agonists,
pubmed-meshheading:12717512-Male,
pubmed-meshheading:12717512-Maze Learning,
pubmed-meshheading:12717512-Memantine,
pubmed-meshheading:12717512-Memory,
pubmed-meshheading:12717512-Rats,
pubmed-meshheading:12717512-Rats, Wistar,
pubmed-meshheading:12717512-Receptors, AMPA
|
pubmed:year |
2003
|
pubmed:articleTitle |
Comparison of the effect of NT-0409 and antidementia drugs on learning and memory in rats with chronic cerebral cholinergic deficiency.
|
pubmed:affiliation |
Laboratory of Neurochemistry, Institute of Physiologically Active Substances, Russian Academy of Sciences, Chernogolovka. nnlermon@mail.ru
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|