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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2003-4-28
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pubmed:abstractText |
LF 15-0195 (LF), a novel analogue of 15-deoxyspergualin (DSG), inhibits maturation of dendritic cells (DC). Anti-CD45RB is a monoclonal antibody (mAb) that blocks activation of T-helper (Th) 1 cells and generates T-regulatory cells. This study addressed whether these two reagents act synergistically to inducing tolerance, and investigated associated cellular mechanisms.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
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pubmed:issn |
0041-1337
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pubmed:author |
pubmed-author:DutartrePatrickP,
pubmed-author:GarciaBerthaB,
pubmed-author:HuangXuyanX,
pubmed-author:IchimThomas ETE,
pubmed-author:JevnikarAnthony MAM,
pubmed-author:MinWei-PingWP,
pubmed-author:StrejanGill HGH,
pubmed-author:XiaXiaopingX,
pubmed-author:YangJinmingJ,
pubmed-author:ZhangXiaoX,
pubmed-author:ZhongRobertR,
pubmed-author:ZhouDejunD
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
75
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1160-5
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:12717196-Animals,
pubmed-meshheading:12717196-Antibodies, Monoclonal,
pubmed-meshheading:12717196-Antigens, CD45,
pubmed-meshheading:12717196-Bone Marrow Cells,
pubmed-meshheading:12717196-Cell Polarity,
pubmed-meshheading:12717196-Dendritic Cells,
pubmed-meshheading:12717196-Drug Synergism,
pubmed-meshheading:12717196-Guanidines,
pubmed-meshheading:12717196-Heart,
pubmed-meshheading:12717196-Heart Transplantation,
pubmed-meshheading:12717196-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:12717196-Male,
pubmed-meshheading:12717196-Mice,
pubmed-meshheading:12717196-Mice, Inbred Strains,
pubmed-meshheading:12717196-Phenotype,
pubmed-meshheading:12717196-Spleen,
pubmed-meshheading:12717196-T-Lymphocytes,
pubmed-meshheading:12717196-T-Lymphocytes, Helper-Inducer,
pubmed-meshheading:12717196-Transplantation, Heterotopic,
pubmed-meshheading:12717196-Transplantation, Homologous,
pubmed-meshheading:12717196-Transplantation Tolerance
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pubmed:year |
2003
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pubmed:articleTitle |
Synergistic tolerance induced by LF15-0195 and anti-CD45RB monoclonal antibody through suppressive dendritic cells.
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pubmed:affiliation |
Department of Surgery, University of Western Ontario, London, Ontario, Canada. mweiping@uwo.ca.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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