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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2003-4-24
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pubmed:abstractText |
E-cadherin (E-cad) is a cell adhesion molecule that is expressed in normal breast tissue. While loss of E-cad expression is a characteristic feature of lobular carcinoma, it also is observed in infiltrating ductal carcinoma (IDC). The presence of peritumoral intralymphatic emboli also is a poor prognostic feature in IDC. Invasive lobular carcinoma rarely is associated with intralymphatic emboli. In the current study, the authors assessed E-cad expression in cases of IDC with and without intralymphatic tumor emboli to examine the potential role played by these molecules in the development of lymphatic emboli.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:copyrightInfo |
Copyright 2003 American Cancer Society.DOI 10.1002/cncr.11332
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2341-7
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:12712492-Adult,
pubmed-meshheading:12712492-Aged,
pubmed-meshheading:12712492-Aged, 80 and over,
pubmed-meshheading:12712492-Breast Neoplasms,
pubmed-meshheading:12712492-Cadherins,
pubmed-meshheading:12712492-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:12712492-Carcinoma, Lobular,
pubmed-meshheading:12712492-Carcinoma in Situ,
pubmed-meshheading:12712492-Female,
pubmed-meshheading:12712492-Humans,
pubmed-meshheading:12712492-Immunoenzyme Techniques,
pubmed-meshheading:12712492-Lymph Nodes,
pubmed-meshheading:12712492-Lymphatic Metastasis,
pubmed-meshheading:12712492-Middle Aged,
pubmed-meshheading:12712492-Neoplasm Staging,
pubmed-meshheading:12712492-Receptor, erbB-2,
pubmed-meshheading:12712492-Receptors, Estrogen,
pubmed-meshheading:12712492-Receptors, Progesterone,
pubmed-meshheading:12712492-Tumor Suppressor Protein p53
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pubmed:year |
2003
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pubmed:articleTitle |
Role of E-cadherins in development of lymphatic tumor emboli.
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pubmed:affiliation |
Department of Pathology, Northwestern University, Chicago, Illinois, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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