Source:http://linkedlifedata.com/resource/pubmed/id/12710312
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2 Pt 1
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| pubmed:dateCreated |
2003-4-24
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| pubmed:abstractText |
This study is designed to assess the value of heart rate turbulence (HRT) in the acute phase of MI for prediction of long-term mortality risk. The study included 128 consecutive acute MI patients with 24-hour Holter recordings to evaluate HRT (turbulence onset and slope), SDNN, mean RR interval, and ventricular premature beat frequency. LVEF was evaluated by two-dimensional echocardiography. Data from 117 patients (mean age 58 +/- 11 years) were available for further analysis. Twelve patients died during follow-up (mean 312 +/- 78 days). Although SDNN < 70 ms was the most powerful predictor of mortality among all presumed risk factors (hazard ratio 20 [95% CI 2.6-158]; P = 0.004) in univariate Cox regression analysis, in multivariate analysis LVEF < or = 0.40 and turbulence slope < or = 2.5 ms/RR interval were the only independent predictors of mortality (hazard ratio 6.9 [95% CI 1.8-26]; P = 0.006, hazard ratio 7.3 [95% CI 1.4-37]; P = 0.016, respectively). Addition of HRT parameters for LVEF increased remarkably the positive predictive value (60%) without any decrease in the negative predictive value (92%). Blunted HRT reaction within the first 24 hours of acute MI is an independent predictor of long-term mortality. Furthermore, its predictive power is comparable and also additive to that of LVEF.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Feb
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| pubmed:issn |
0147-8389
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| pubmed:author |
pubmed-author:AksöyekSerdarS,
pubmed-author:AlyR HRH,
pubmed-author:AytemirKudretK,
pubmed-author:KabakçiGirayG,
pubmed-author:KesSirriS,
pubmed-author:NazliNashN,
pubmed-author:OvünçKenanK,
pubmed-author:OzerNeclaN,
pubmed-author:OzkutluHilmiH,
pubmed-author:OzmenFerhanF,
pubmed-author:SadeElifE,
pubmed-author:TokgözogluLaleL
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| pubmed:issnType |
Print
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| pubmed:volume |
26
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
544-50
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| pubmed:dateRevised |
2004-11-17
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| pubmed:meshHeading |
pubmed-meshheading:12710312-Case-Control Studies,
pubmed-meshheading:12710312-Diabetes Mellitus,
pubmed-meshheading:12710312-Echocardiography,
pubmed-meshheading:12710312-Electrocardiography, Ambulatory,
pubmed-meshheading:12710312-Female,
pubmed-meshheading:12710312-Heart Rate,
pubmed-meshheading:12710312-Humans,
pubmed-meshheading:12710312-Male,
pubmed-meshheading:12710312-Middle Aged,
pubmed-meshheading:12710312-Multivariate Analysis,
pubmed-meshheading:12710312-Myocardial Infarction,
pubmed-meshheading:12710312-Predictive Value of Tests,
pubmed-meshheading:12710312-Prognosis,
pubmed-meshheading:12710312-Regression Analysis,
pubmed-meshheading:12710312-Risk Factors,
pubmed-meshheading:12710312-Sensitivity and Specificity,
pubmed-meshheading:12710312-Stroke Volume,
pubmed-meshheading:12710312-Time Factors,
pubmed-meshheading:12710312-Ventricular Premature Complexes
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| pubmed:year |
2003
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| pubmed:articleTitle |
Assessment of heart rate turbulence in the acute phase of myocardial infarction for long-term prognosis.
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| pubmed:affiliation |
Hacettepe University School of Medicine, Department of Cardiology, Ankara, Turkey. sadele@msx.upmc.edu
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| pubmed:publicationType |
Journal Article
|