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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-4-23
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pubmed:abstractText |
The pharmacokinetics of colistin was investigated using specific high-performance liquid chromatography (HPLC) to measure the concentrations of colistin and colistin A and B in plasma and urine in five rats after administration of an intravenous bolus of 1 mg of colistin sulfate/kg of body weight. There were differences in the pharmacokinetic behaviors of unbound colistin A and B. This is the first report of the use of HPLC to study the pharmacokinetics of colistin and its two major components.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-10348745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-10452626,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-10492501,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-10926333,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-11129122,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-11402633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-11439002,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-11560379,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-11587924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-11706322,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-12654671,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-14008070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-14928233,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-1809216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-4357724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-5448745,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-6284955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-7682274,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-8860068,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-9397540,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-9402364,
http://linkedlifedata.com/resource/pubmed/commentcorrection/12709357-9795682
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0066-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1766-70
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:12709357-Animals,
pubmed-meshheading:12709357-Anti-Bacterial Agents,
pubmed-meshheading:12709357-Chromatography, High Pressure Liquid,
pubmed-meshheading:12709357-Colistin,
pubmed-meshheading:12709357-Injections, Intravenous,
pubmed-meshheading:12709357-Male,
pubmed-meshheading:12709357-Metabolic Clearance Rate,
pubmed-meshheading:12709357-Protein Binding,
pubmed-meshheading:12709357-Rats,
pubmed-meshheading:12709357-Rats, Sprague-Dawley
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pubmed:year |
2003
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pubmed:articleTitle |
Use of high-performance liquid chromatography to study the pharmacokinetics of colistin sulfate in rats following intravenous administration.
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pubmed:affiliation |
Centre for Pharmaceutical Research. School of Pharmaceutical, Molecular and Biomedical Sciences, University of South Australia, Adelaide, Australia.
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pubmed:publicationType |
Journal Article
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