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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5-6
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pubmed:dateCreated |
2003-4-22
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pubmed:abstractText |
A new glucose biosensor has been fabricated by immobilizing glucose oxidase into a copper dispersed sol-gel derived ceramic-graphite composite. The copper in the biocomposite offers excellent electrocatalytic activity towards the reduction (at -0.2 V) as well as oxidation (at +0.45 V) of hydrogen peroxide liberated in the enzymatic reaction enabling sensitive and selective determination of glucose. A linear response to glucose in the concentration range between 2.7 x 10(-5) to 4.0 x 10(-3) M with a correlation coefficient of 0.9987 and 4.0 x 10(-5) to 5.6 x 10(-3) M with a correlation coefficient of 0.9989 were observed with the electrocatalytic reduction and oxidation, respectively. Ascorbic acid and uric acid did not interfere with the glucose measurement during catalytic reduction at -0.2 V, a Nafion membrane was used to eliminate these interferences during the electrocatalytic oxidation at +0.45 V. The combination of copper catalysis and the promising feature of sol-gel biocomposite favor the sensitive and selective determination of glucose with improved analytical capabilities.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/(3-mercaptopropyl)trimethoxysilane,
http://linkedlifedata.com/resource/pubmed/chemical/Ceramics,
http://linkedlifedata.com/resource/pubmed/chemical/Coated Materials, Biocompatible,
http://linkedlifedata.com/resource/pubmed/chemical/Copper,
http://linkedlifedata.com/resource/pubmed/chemical/Enzymes, Immobilized,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorocarbon Polymers,
http://linkedlifedata.com/resource/pubmed/chemical/Gels,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose Oxidase,
http://linkedlifedata.com/resource/pubmed/chemical/Graphite,
http://linkedlifedata.com/resource/pubmed/chemical/Hydrogen Peroxide,
http://linkedlifedata.com/resource/pubmed/chemical/Silanes,
http://linkedlifedata.com/resource/pubmed/chemical/perfluorosulfonic acid
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0956-5663
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
721-8
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pubmed:dateRevised |
2009-7-14
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pubmed:meshHeading |
pubmed-meshheading:12706584-Biosensing Techniques,
pubmed-meshheading:12706584-Ceramics,
pubmed-meshheading:12706584-Coated Materials, Biocompatible,
pubmed-meshheading:12706584-Copper,
pubmed-meshheading:12706584-Electrochemistry,
pubmed-meshheading:12706584-Enzymes, Immobilized,
pubmed-meshheading:12706584-Equipment Failure Analysis,
pubmed-meshheading:12706584-Fluorocarbon Polymers,
pubmed-meshheading:12706584-Gels,
pubmed-meshheading:12706584-Glucose,
pubmed-meshheading:12706584-Glucose Oxidase,
pubmed-meshheading:12706584-Graphite,
pubmed-meshheading:12706584-Hydrogen Peroxide,
pubmed-meshheading:12706584-Phase Transition,
pubmed-meshheading:12706584-Reproducibility of Results,
pubmed-meshheading:12706584-Sensitivity and Specificity,
pubmed-meshheading:12706584-Silanes
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pubmed:year |
2003
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pubmed:articleTitle |
A metal dispersed sol-gel biocomposite amperometric glucose biosensor.
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pubmed:affiliation |
Satellite Venture Business Laboratory, Utsunomiya University, Yoto 7-1-2, 321-8585, Utsunomiya, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
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