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pubmed:abstractText |
Hypothalamic serotonin, the synthesis of which parallels plasma free tryptophan, contributes to satiety. Plasma free tryptophan, insulin and leptin, all of which can also decrease food intake partly via the hypothalamic serotonergic system, are modulated by cytokines, which decrease food intake. The mechanisms of anorexia induced by cytokines, as related to plasma tryptophan, leptin and insulin, have not been fully determined.
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pubmed:affiliation |
Surgical Metabolism and Nutrition Laboratory, Department of Surgery, SUNY Upstate Medical University, Syracuse, NY 13210, USA.
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