12698077

Source:http://linkedlifedata.com/resource/pubmed/id/12698077

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0018787, umls-concept:C0026336, umls-concept:C0034693, umls-concept:C0034721, umls-concept:C0035015, umls-concept:C0074568, umls-concept:C0205191, umls-concept:C0450127, umls-concept:C1533157, umls-concept:C1548437, umls-concept:C1820201, umls-concept:C1882923
pubmed:issue	7
pubmed:dateCreated	2003-4-16
pubmed:abstractText	Chronic rejection (CR) with graft vasculopathy is recognized as a major cause of graft loss over time. Sinomenine (SN) has anti-inflammatory, antirheumatic, and immunomodulatory effects. Previously, we demonstrated antimacrophage and anti-T cell effects of SN in acute rejection. In the current study, we investigated the effect of SN in a rat cardiac allograft model of CR.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0132144
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Adjuvants, Immunologic, http://linkedlifedata.com/resource/pubmed/chemical/Cyclosporine, http://linkedlifedata.com/resource/pubmed/chemical/Cytokines, http://linkedlifedata.com/resource/pubmed/chemical/Growth Substances, http://linkedlifedata.com/resource/pubmed/chemical/Immunosuppressive Agents, http://linkedlifedata.com/resource/pubmed/chemical/Morphinans, http://linkedlifedata.com/resource/pubmed/chemical/sinomenine
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0041-1337
pubmed:author	pubmed-author:AmbergerAlbertA, pubmed-author:CandinasDanielD, pubmed-author:MargreiterRaimundR, pubmed-author:MarkWalterW, pubmed-author:OffnerFelixF, pubmed-author:SchneebergerStefanS, pubmed-author:SeilerRüdigerR, pubmed-author:StrokaDeborah MDM
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	75
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	940-5
pubmed:dateRevised	2003-11-14
pubmed:meshHeading	pubmed-meshheading:12698077-Adjuvants, Immunologic, pubmed-meshheading:12698077-Animals, pubmed-meshheading:12698077-Antibody Formation, pubmed-meshheading:12698077-Chronic Disease, pubmed-meshheading:12698077-Cyclosporine, pubmed-meshheading:12698077-Cytokines, pubmed-meshheading:12698077-Drug Therapy, Combination, pubmed-meshheading:12698077-Graft Rejection, pubmed-meshheading:12698077-Growth Substances, pubmed-meshheading:12698077-Heart, pubmed-meshheading:12698077-Heart Transplantation, pubmed-meshheading:12698077-Immunosuppressive Agents, pubmed-meshheading:12698077-Male, pubmed-meshheading:12698077-Morphinans, pubmed-meshheading:12698077-Myocardium, pubmed-meshheading:12698077-Rats, pubmed-meshheading:12698077-Rats, Inbred F344, pubmed-meshheading:12698077-Transplantation, Homologous, pubmed-meshheading:12698077-Ventricular Remodeling
pubmed:year	2003
pubmed:articleTitle	Sinomenine blocks tissue remodeling in a rat model of chronic cardiac allograft rejection.
pubmed:affiliation	Department of Transplant Surgery, University Hospital Innsbruck, Anichstrasse 35, A-6020 Innsbruck, Austria. Walter.Mark@uibk.ac.at
pubmed:publicationType	Journal Article, Validation Studies