Linked Life Data

12697287

Source:http://linkedlifedata.com/resource/pubmed/id/12697287

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2003-4-16
pubmed:abstractText
Selenium compounds display antioxidant and neuroprotective properties. Diphenyl diselenide (PhSe)(2) is an organic selenium compound that affects a number of neuronal processes. The aim of the present study was to evaluate the effects of the systemic administration of (PhSe)(2) on novel object recognition memory in mice. Adult male CF1 mice were given an i.p. injection of (PhSe)(2) (0.2, 1.0, 5.0, or 25.0 micromol/kg) 30 min before training in an object recognition task. (PhSe)(2) did not affect short-term memory or the total time exploring both objects, but induced a facilitation of retention measured 24 h after training. The present findings show that systemic administration of (PhSe)(2) induces a facilitation of formation of long-term object recognition memory.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
341
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
217-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Facilitation of long-term object recognition memory by pretraining administration of diphenyl diselenide in mice.
pubmed:affiliation
GENOTOX Laboratory, Center for Biotechnology, Universidade Federal do Rio Grande do Sul (UFRGS), 91501-970 Porto Alegre, Brazil.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't