rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
17
|
pubmed:dateCreated |
2003-5-6
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pubmed:abstractText |
Coronary artery spasm plays an important role in the pathogenesis of ischemic heart diseases such as unstable angina (UA) and acute myocardial infarction. Nitric oxide (NO) plays an important role in coronary artery spasm. We previously reported a deficiency in NO activity in the spasm arteries of patients with coronary spastic angina (CSA). Others have reported that NO influences the immune response. Therefore, we investigated the balance between T-helper type 1 (Th1) and 2 (Th2) responses in patients with CSA by evaluating the frequencies of interferon (IFN)-gamma-producing T cells and interleukin (IL)-4-producing T cells in the peripheral blood of such patients.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
May
|
pubmed:issn |
1524-4539
|
pubmed:author |
pubmed-author:HokamakiJunJ,
pubmed-author:IrieAtsushiA,
pubmed-author:KajiwaraIchiroI,
pubmed-author:KojimaSunaoS,
pubmed-author:MiyamotoShinzoS,
pubmed-author:NishimuraYasuharuY,
pubmed-author:OgawaHisaoH,
pubmed-author:SakamotoTomohiroT,
pubmed-author:SoejimaHirofumiH,
pubmed-author:TanakaTomokoT,
pubmed-author:YoshimuraMichihiroM
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pubmed:issnType |
Electronic
|
pubmed:day |
6
|
pubmed:volume |
107
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2196-200
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12695292-Adult,
pubmed-meshheading:12695292-Aged,
pubmed-meshheading:12695292-Angina, Unstable,
pubmed-meshheading:12695292-Angina Pectoris,
pubmed-meshheading:12695292-Coronary Vasospasm,
pubmed-meshheading:12695292-Female,
pubmed-meshheading:12695292-Humans,
pubmed-meshheading:12695292-Interferon-gamma,
pubmed-meshheading:12695292-Interleukin-4,
pubmed-meshheading:12695292-Male,
pubmed-meshheading:12695292-Middle Aged,
pubmed-meshheading:12695292-Nitric Oxide Donors,
pubmed-meshheading:12695292-Th1 Cells,
pubmed-meshheading:12695292-Th2 Cells
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pubmed:year |
2003
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pubmed:articleTitle |
Preference toward a T-helper type 1 response in patients with coronary spastic angina.
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pubmed:affiliation |
Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Honjo, Kumamoto City 860-8556, Japan. yuuki@gpo.kumamoto-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|