| pubmed-article:12695157 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0028128 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0021753 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0039099 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0040284 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C1456820 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0205177 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0063041 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0870883 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C0033268 | lld:lifeskim |
| pubmed-article:12695157 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:12695157 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:12695157 | pubmed:dateCreated | 2003-4-15 | lld:pubmed |
| pubmed-article:12695157 | pubmed:abstractText | Leflunomide is now an approved agent for the management of adult rheumatoid arthritis (RA). Its active metabolite A771726 inhibits de novo pyrimidine biosynthesis. Although considered to be an immunosuppressive agent, its mechanism of action remains obscure. | lld:pubmed |
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| pubmed-article:12695157 | pubmed:language | eng | lld:pubmed |
| pubmed-article:12695157 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:12695157 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:12695157 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:12695157 | pubmed:month | May | lld:pubmed |
| pubmed-article:12695157 | pubmed:issn | 0003-4967 | lld:pubmed |
| pubmed-article:12695157 | pubmed:author | pubmed-author:YaronMM | lld:pubmed |
| pubmed-article:12695157 | pubmed:author | pubmed-author:YaronII | lld:pubmed |
| pubmed-article:12695157 | pubmed:author | pubmed-author:CaspiDD | lld:pubmed |
| pubmed-article:12695157 | pubmed:author | pubmed-author:ElkayamOO | lld:pubmed |
| pubmed-article:12695157 | pubmed:author | pubmed-author:ShiraziII | lld:pubmed |
| pubmed-article:12695157 | pubmed:author | pubmed-author:JudovitchRR | lld:pubmed |
| pubmed-article:12695157 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:12695157 | pubmed:volume | 62 | lld:pubmed |
| pubmed-article:12695157 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:12695157 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:12695157 | pubmed:pagination | 440-3 | lld:pubmed |
| pubmed-article:12695157 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:12695157 | pubmed:year | 2003 | lld:pubmed |
| pubmed-article:12695157 | pubmed:articleTitle | Active leflunomide metabolite inhibits interleukin 1beta, tumour necrosis factor alpha, nitric oxide, and metalloproteinase-3 production in activated human synovial tissue cultures. | lld:pubmed |
| pubmed-article:12695157 | pubmed:affiliation | Department of Rheumatology, Tel Aviv Sourasky Medical Center, Israel. oribe14@netvision.net.il | lld:pubmed |
