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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2003-5-5
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pubmed:abstractText |
Hypercholesterolemia is associated with endothelial dysfunction. Inducible nitric oxide synthase (iNOS) is upregulated in atherosclerotic vessels. However, its role in the regulation of vascular function is not completely understood. We examined the effect of adenovirus-mediated gene transfer of iNOS to the hypercholesterolemic rabbit carotid artery in vivo.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/1,2-Dihydroxybenzene-3,5-Disulfonic...,
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, Dietary,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase,
http://linkedlifedata.com/resource/pubmed/chemical/Nitric Oxide Synthase Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Phenylephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Fusion Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Superoxides,
http://linkedlifedata.com/resource/pubmed/chemical/Vasoconstrictor Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Vasodilator Agents
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4628
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1293-8
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:12690222-1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt,
pubmed-meshheading:12690222-Acetylcholine,
pubmed-meshheading:12690222-Adenoviridae,
pubmed-meshheading:12690222-Animals,
pubmed-meshheading:12690222-Carotid Arteries,
pubmed-meshheading:12690222-Cholesterol, Dietary,
pubmed-meshheading:12690222-Cytomegalovirus,
pubmed-meshheading:12690222-Diet, Atherogenic,
pubmed-meshheading:12690222-Endothelium, Vascular,
pubmed-meshheading:12690222-Gene Therapy,
pubmed-meshheading:12690222-Genes, Reporter,
pubmed-meshheading:12690222-Genetic Vectors,
pubmed-meshheading:12690222-Hypercholesterolemia,
pubmed-meshheading:12690222-Lac Operon,
pubmed-meshheading:12690222-Nitric Oxide Synthase,
pubmed-meshheading:12690222-Nitric Oxide Synthase Type II,
pubmed-meshheading:12690222-Phenylephrine,
pubmed-meshheading:12690222-Promoter Regions, Genetic,
pubmed-meshheading:12690222-Rabbits,
pubmed-meshheading:12690222-Recombinant Fusion Proteins,
pubmed-meshheading:12690222-Superoxides,
pubmed-meshheading:12690222-Transduction, Genetic,
pubmed-meshheading:12690222-Vasoconstrictor Agents,
pubmed-meshheading:12690222-Vasodilation,
pubmed-meshheading:12690222-Vasodilator Agents
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pubmed:year |
2003
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pubmed:articleTitle |
In vivo gene transfer of inducible nitric oxide synthase to carotid arteries from hypercholesterolemic rabbits.
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pubmed:affiliation |
Department of Endocrinology, Mayo Clinic and Foundation, Rochester, Minn., USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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