Linked Life Data

12689549

Source:http://linkedlifedata.com/resource/pubmed/id/12689549

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2003-4-11
pubmed:abstractText
The etiology of neural tube defects (NTDs) is multifactorial. The presence of mutated genotypes of C677T and A1298C polymorphisms, and their combined heterozygosity, have been considered risk factors for the occurrence and recurrence of NTDs in some populations. Subjects and method: This case-control study included 159 healthy controls, 27 NTDs patients, 28 patients' mothers and 23 siblings. The polymorphism study was performed by PCR. For fragment digestion, we used the restriction enzymes Hinf I (C677T) and Mbo II (A1298C).
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0025-7753
pubmed:author
pubmed:issnType
Print
pubmed:day
5
pubmed:volume
120
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
441-5
pubmed:dateRevised
2009-11-3
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
[C677T and A1298C MTHFR polymorphisms in the etiology of neural tube defects in Spanish population].
pubmed:affiliation
Sección de Genética. Servicio de Bioquímica Clínica. Hospital Universitario Miguel Servet. Zaragoza. España. joseignaciogutierrez@redfarma.org
pubmed:publicationType
Journal Article, English Abstract