rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9364
|
pubmed:dateCreated |
2003-4-10
|
pubmed:abstractText |
The diagnosis of latent tuberculosis infection relies on the tuberculin skin test (TST), which has many drawbacks. However, to find out whether new tests are better than TST is difficult because of the lack of a gold standard test for latent infection. We developed and assessed a sensitive enzyme-linked immunospot (ELISPOT) assay to detect T cells specific for Mycobacterium tuberculosis antigens that are absent from Mycobacterium bovis BCG and most environmental mycobacteria. We postulated that if the ELISPOT is a more accurate test of latent infection than TST, it should correlate better with degree of exposure to M tuberculosis.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0140-6736
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
5
|
pubmed:volume |
361
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1168-73
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:12686038-Adolescent,
pubmed-meshheading:12686038-BCG Vaccine,
pubmed-meshheading:12686038-Child,
pubmed-meshheading:12686038-Disease Outbreaks,
pubmed-meshheading:12686038-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:12686038-Female,
pubmed-meshheading:12686038-Great Britain,
pubmed-meshheading:12686038-Humans,
pubmed-meshheading:12686038-Male,
pubmed-meshheading:12686038-Mycobacterium tuberculosis,
pubmed-meshheading:12686038-Tuberculin Test,
pubmed-meshheading:12686038-Tuberculosis
|
pubmed:year |
2003
|
pubmed:articleTitle |
Comparison of T-cell-based assay with tuberculin skin test for diagnosis of Mycobacterium tuberculosis infection in a school tuberculosis outbreak.
|
pubmed:affiliation |
Nuffield Department of Clinical Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|