Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2003-4-9
pubmed:abstractText
Many plant substances are known for their interference with the reproductive system. Mikania glomerata is a plant popularly used to treat respiratory diseases and is reported to have flavonoids and coumarin, which have been shown to have antifertility activity in male dogs and female rats, respectively. This work analyzes the effect of a high dose of M. glomerata extract administered during the spermatogenic cycle of rats. Adult Wistar rats were treated with 1 mL of a M. glomerata extract at a dose level of 3.3 g/kg of body weight for 52 days. Body and organ weights, sperm production, circulating testosterone level and food consumption were evaluated. The results showed that the administration of the M. glomerata extract during the rat spermatogenic cycle did not significantly alter the body and organ weights nor did it interfere with gamete production, serum testosterone level or food intake.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0010-7824
pubmed:author
pubmed:issnType
Print
pubmed:volume
67
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
327-31
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
2003
pubmed:articleTitle
Evaluation of long-term exposure to Mikania glomerata (Sprengel) extract on male Wistar rats' reproductive organs, sperm production and testosterone level.
pubmed:affiliation
Biology Department, Federal University of Juiz de Fora, Juiz de Fora, 36036-330, MG, Brazil. ritacassia.sa@bol.com.br
pubmed:publicationType
Journal Article